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H$f.$v!I0MMIIEH$H$HDHHH IH$XHlH$XH \$D$BH$H$0H$ H$8H$HH$HDHcHLxL$HD$H$f)T$ HcHHDHL$@H$s[$HD$HHL$@$DX$$HH$j_$HZ$L$X$H$PH;f(T$ H$HH.$H$@$X$P$$X$H$$X$@$$^$$(f.$I0HDŽ$L$DHHH7L:fTf.H$~8H$HH$Hu H$X$XfW$P$Pf.$uzH$8u HǀH2H=u2H=u2H=u2H=}ux2H=Yul2H=Eu`2H=quT2H=]uH2'A9|&fDAD9HH$($lI}HtAMDH$H$H$ $uIEAH$Ht$HcHDH$$~DH$(juHAH$HHt$HcHDH$$~H$xH$pHcDdIcĉ\m.5uH$H=sHcH:5tH$H=sHsHcHHps|11$TAH !+C1H$HH$)H$H$f)L$wHEH$$ f(L$HE0fTH$`f.ыE8D 5sH119@ǃH9|H$*HsH$$$Y$$$ X$$$ ^$$$\N$H$HIL%qi$H$I$IL%qpi$H$I$tIL%uqd$H$I$IL%BqUd$H$I$IL%qu$`H$`I$IL%pt$hH$hI$IL%pjn$8H$8I$IL%p?n$@H$@I$c$ ϓC],Hc=qH$HIĉ0HbqA)9|HH-AqHH9t9 HcD\HcD/ͿC1+A<$Ih,DD)9pH5oC1+H,H$HH$jCH$VH$-<PC_H$VH$EJ-C?H$VH$-H$0C&H$HǀP5oH119@ǃH9|$ H$5o*HoXCH$X$`$`Y$X$P$ X$P$Hf(^$H$@$@\.$8$`$8Y$H$f(\$$$$H)"nDHHHbmC?H$VH$l+H$C@t@tf1t ftH$V+БCH$H$V*“C ffffff.H\$Hl$HLd$6eCH(H%)HtH\$Hl$Ld$ H(@H=a"L)HIA)I|H輞H5="IH2*HLw)6eCL(HtLHD$(HD$끾CHL)V)f.AUATIUHSHH!HH5!JH!H=!L1IHH!%)LHH)H5u!HH(Ht5 H(HuCH5L!H?wHH59!H!!H9HDH[]A\HA]@H H[]A\HA]ÿH KHH  fff.SHHH;(u CHuH8jH$$H[fHT$H߾C1'HD$H$$H[AWIAVAUATUHLSHH(AI@IE,$D_(uA0A w/fIA<$GЃ vDIA<$"(uMIA} (tA CAELL0H9iHD$HD$HEIA}'uLH}'tELLHhHD$HD$HH] fDH+@`'uI@uDP&uMIE<$D%uEA$LH%CI\$f.HD#A%uIEucAE CHumHgHD$HD$HE1H[]A\A]A^A_LHx%CvIEeAf%uHH߾C1$H1[]A\A]A^A_ffff.AWAVAUATUSHH$VHt$8"¸tH[]A\A]A^A_H$f#Ht$8HxH$HHVQ$Ht$8CHt$8mCH$HDŽ$@WH$HHDŽ$8kD$|H$@H$8D$LH$H$HcL$L1H H HHL$h|$|H\$hH$AA HcH L$1LL$IMEu  H eHUH$H$I $HIIIurD$L|$LID$|H$@H$8|$|H$#H$#Ht$8C!Ht$8*CH$ HDŽ$PH$HHDŽ$HD$xH$PH$HD$HH$H$HcL$H1H H HHL$`|$xH\$`H$AA HcH L$1LL$IMEu  H cHUH$H$I $HIIIurD$H|$HBD$xH$PH$H|$xH$!H$!Ht$85CHt$8?CH$HDŽ$`H$HHDŽ$XDŽ$4H$`H$X1H$(H$ 1$4L$(LcÃAIML$ A 1ELMtfDHcMHLH4L4Hc5 HH5H~Hڃ0$wT HH9uH$H$H$D9HFH`|$L@Ht$8H$D$HT$$H$Ht$8H$IM$D$HT$ّ$AIMH$$fTf.rfT f.H ZHIuH$H$If|$HHt$8H$D$HT$$H$Ht$8H$IM$D$HT$$AIMH$$fTf.rfT f.`HIMH YH$H$I3fu#MMMM@|$@tHt$8H$HD$T$L$LD$0LL$(LT$ $(H$(H$IuHt$8$ HD$T$L$$ LD$0LL$(IuLT$ H$$fTf.rfT f.HIuH5XH$H$H0|$DHt$8H$HD$T$L$LD$0LL$(LT$ $HH$HH$IuHt$8$@HD$T$ݎL$$@LD$0LL$(IuLT$ H$8$8fTf.rfT f.:H5WHI}H$H$H0 Ht$8H$D$HT$HL$$hH$hH$HuHt$8$`D$HT$HL$$`AHuH$X$XfTf.rfT f.H5VILEH$H$I6fHt$8H$D$HT$HL$ $H$H$HuHt$8$xD$HT$HL$$xAHuH$p$pfT?f.rfT 1f.H5VILUH$H$I6EH=LIcHaHHc5HT$8L$H=ACH!LHHt$8CHT$8Io2L|$8HfXHcMHLH4L"Hc5*HH5'H~Hڃ0$wT HH9uH$H$H$D9HFt HdEH=LIcHH9Hc5HT$8L$H=ACHLHaHt$8CHT$8IAL|$8H@*f.Hc1MHLH4LHc5HH5H~Hڃ0$wT HH9uH$H$H$D9HFt HdEH=LIcH~Ht/Hc5XHT$8L$H=TACH~LH1THt$8CmHT$8I蜡L|$8Hf.Hc1MHLH4LHc5HH5H~Hڃ0$wT HH9uH$bH$H$D9FHFt HAdEH=2LIcH{}H/Hc5HT$8H= HI}LH1Hdy=HTHHHHH(H=uH@ 1HH[}(108@HTHHHHH(H=uH0@H3|H1fWHf.u2z0f(f.w,f(_\Qf.z(u&Y.HÐf.vHDf(YDSH )ʃt}~{HHHH@D$pT$`f.MGHH(Yi?HEH@!?H-H=~H5gHXH yHZH;D$pEd$ l$0t$@ ;YD$pX 1L$PYL$PXYD$xXD$pL$PYD$pXT$YAT$Y*L$PXt$@l$0d$ YXAD$h^qL$Pd$ l$0t$@ Y,l$0d$ t$@L$Pf(X^^f(X^f(\܃@T@G@Cn 1H@Au̓:H1H@Au$fD1OH@A@Tt@G@C@NH~PfD1H@Au fD1[H@At{@Tt@GZ@C>@NGBf)D)sH<TA1@C{@NU@CM@NP_f(d$ f(l$0XD$`^kf(D$hL$P^Yl$0d$ L$PY ́X^\ f(XVZNN|NN&jwH@NNe@N[A7THG[N1UPP~U:f(d$ f(l$0XD$`^e(A*Al$0d$ Y KYXD$hL$P^1d$ YVL$Pd$ X^f(\bo \^T$pR8D$h^x*QD$pf.zt/D$pd$ l$0t$@t$@l$0d$ L$`^ @^L$`f.f(d$ l$0t$@D$pD$`L$xYY Dd$ l$0Y@t$@\ *Y ~YL$pX2D$hL$P^~wfW5sf(of.HI(Yi?IEI@!?H0L-!L% LLL LQL$`f.zt3D$`d$ l$0t$@t$@f(l$0d$ D$`d$ l$0t$@L$PVL$PY ~YD$`X ~Y } n!f(D$`L$P L$PYY }Y}X }XD$`Y } f(D$`T$ }T$Y}Y}t$@l$0d$ X}XY-}}=H\$Hl$Ld$Ll$HHHD$A $AT$\$ v$qH\$(Hl$0Ld$8Ll$@HHAwA9|=\$DT$ $HD$H\$(Hl$0Ld$8Ll$@HHT$HL$H\$($Hl$0Ld$8Ll$@1HHfffff.Hl$Ld$H- L% Ll$Lt$L|$H\$H8L)AIHIHt1@LLDAHH9rH\$Hl$Ld$Ll$ Lt$(L|$0H8ÐUHSHH HtcDHHHuH[ÐHH./primer3_config/opt/primer3_config[-io_version=3|-io_version=4][-format_output][input_file][-error=][-output=][-strict_tags][-echo_settings_file]This is primer3 (%s) For example: aboutformat_outputstrict_tagsp3_settings_fileecho_settings_fileio_versiondefault_versionDump_args2x_compaterror42Error creating file %s Error opening file %s %s: %s Left primerRight primerHybridization probe%s: received signal %d [-default_version=1|-default_version=2 USAGE: %s %s %s %s %s %s %s %s %s %s [-p3_settings_file=]Input can also be provided on standard input. $ primer3_core < my_input_file PRIMER_ERROR=flag -2x_compat is no longer supported =PRIMER_ERROR=thermodynamic approach chosen, but path to thermodynamic parameters not specified =Need PRIMER_SEQUENCE_ID if PRIMER_FILE_FLAG is not 0 @@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@h@@@@8@@@@@@@@WARNINGS FOR %s INPUT PROBLEM: %s rep %s (start, len)*: %d,%d %5.2f %5s PRODUCT SIZE: %d, PRODUCT Tm: %.4f, LeftRight %6d%6d%6d%6d Statistics toocontmnonot high%6s%6slower%6s tarmanysid3'badokexcl3'_th any_thhair-poly caseeredGC%reg complsimstabok IntlPair Stats: %s %5d %5d %s %s %5d %s ...... vector sequence XXXXXX excluded region ****** target >>>>>> left primer <<<<<< right primer ^^^^^^ internal oligo PAIR_OK_REGIONS ,, %d,%d,__null != fformat_output.c__null != saUsing mispriming library %s NO PRIMERS FOUND WARNING: %s LEFT PRIMERRIGHT PRIMERINTERNAL OLIGOSEQUENCE SIZE: %d INCLUDED REGION SIZE: %d TARGETSEXCLUDED REGIONSADDITIONAL OLIGOS %2d fflush(f) failedNO LEFT PRIMER FOUND NO INTERNAL OLIGO FOUND NO RIGHT PRIMER FOUND SEQUENCE SIZE: %ld PRIMER PICKING RESULTS FOR %s %-16s start len tm gc%% any 3' %sseq %-16s start len tm gc%% any_th 3'_th hairpin %sseq %-16s %5d %4d %7.2f %7.2f %5.2f %5.2f %-16s %5d %4d %7.2f %7.2f %5.2f %5.2f POSITION PENALTY, QUALITY: %f, %f PAIR ANY COMPL: %.2f, PAIR 3' COMPL: %.2f PAIR ANY_TH COMPL: %.2f, PAIR 3'_TH COMPL: %.2f PRODUCT Tm - min(OLIGO Tm): %.4f %-6s%6d%6d%6d%6d%6d%6d%6d%6d%6d%6s%6s%6s%6s%6s%6s%6s%6s%6s%6s%7s%6s%6s%6s%6s%6s%6s%6s%6s%6s%6s%6s%6s%6sKEYS (in order of precedence): xxxxxx excluded region for internal oligo ^^^^^^ left primer / right primer overlap %s (left_start, left_len, right_start, right_len)*:%s:%s:%d, assertion (%s) failed No mispriming library specified Using internal oligo mishyb library %s No internal oligo mishyb library specified Using %d-based sequence positions INTERNAL OLIGO EXCLUDED REGIONSProgram name is probably primer3_core)C.A.out of memory in read_boulder (value too large or too small) begins but does not end with a quoteError in sequence quality dataPRIMER_INTERNAL_OLIGO_EXCLUDED_REGIONPRIMER_INTERNAL_OLIGO_OPT_SIZEPRIMER_INTERNAL_OLIGO_MAX_SIZEPRIMER_INTERNAL_OLIGO_MIN_SIZEPRIMER_INTERNAL_OLIGO_MAX_POLY_XPRIMER_INTERNAL_OLIGO_OPT_GC_PERCENTPRIMER_INTERNAL_OLIGO_SALT_CONCPRIMER_INTERNAL_OLIGO_DIVALENT_CONCPRIMER_INTERNAL_OLIGO_DNTP_CONCPRIMER_INTERNAL_OLIGO_DNA_CONCPRIMER_INTERNAL_OLIGO_MIN_QUALITYPRIMER_INTERNAL_OLIGO_SELF_ANYPRIMER_INTERNAL_OLIGO_SELF_ENDPRIMER_INTERNAL_OLIGO_MAX_MISHYBPRIMER_MAX_TEMPLATE_MISPRIMINGPRIMER_PAIR_MAX_TEMPLATE_MISPRIMINGPRIMER_LIB_AMBIGUITY_CODES_CONSENSUSDuplicate PRIMER_MISPRIMING_LIBRARY tagDuplicate PRIMER_INTERNAL_OLIGO_MISHYB_LIBRARY tagPRIMER_PAIR_WT_PRODUCT_SIZE_GTPRIMER_PAIR_WT_PRODUCT_SIZE_LTPRIMER_PAIR_WT_TEMPLATE_MISPRIMINGSEQUENCE_PRIMER_PAIR_OK_REGION_LISTSEQUENCE_INTERNAL_EXCLUDED_REGIONError in SEQUENCE_PRIMER_OVERLAP_JUNCTION_LISTPRIMER_MIN_THREE_PRIME_DISTANCEBoth PRIMER_MIN_THREE_PRIME_DISTANCE and PRIMER_{LEFT/RIGHT}_MIN_THREE_PRIME_DISTANCE specifiedPRIMER_MIN_LEFT_THREE_PRIME_DISTANCEPRIMER_MIN_RIGHT_THREE_PRIME_DISTANCEPRIMER_MIN_5_PRIME_OVERLAP_OF_JUNCTIONPRIMER_MIN_3_PRIME_OVERLAP_OF_JUNCTIONPRIMER_INTERNAL_OPT_GC_PERCENTPRIMER_INTERNAL_SALT_MONOVALENTPRIMER_INTERNAL_MAX_NS_ACCEPTEDPRIMER_INTERNAL_MAX_SELF_ANY_THPRIMER_INTERNAL_MAX_SELF_END_THPRIMER_INTERNAL_MAX_HAIRPIN_THPRIMER_INTERNAL_MAX_LIBRARY_MISHYBPRIMER_PAIR_MAX_LIBRARY_MISPRIMINGPRIMER_MAX_TEMPLATE_MISPRIMING_THPRIMER_PAIR_MAX_TEMPLATE_MISPRIMING_THDuplicate PRIMER_INTERNAL_MISHYB_LIBRARY tagPRIMER_THERMODYNAMIC_ALIGNMENTPRIMER_WT_TEMPLATE_MISPRIMING_THPRIMER_INTERNAL_WT_GC_PERCENT_GTPRIMER_INTERNAL_WT_GC_PERCENT_LTPRIMER_INTERNAL_WT_SELF_ANY_THPRIMER_INTERNAL_WT_SELF_END_THPRIMER_INTERNAL_WT_LIBRARY_MISHYBPRIMER_PAIR_WT_LIBRARY_MISPRIMINGPRIMER_PAIR_WT_TEMPLATE_MISPRIMING_THFinal record not terminated by '='pick_pcr_primers_and_hyb_probeContradiction in primer_task definitionPRIMER_INTERNAL_OLIGO_MISHYB_LIBRARYSEQUENCE_OVERLAP_JUNCTION_LISTPRIMER_INTERNAL_MISHYB_LIBRARYPRIMER_THERMODYNAMIC_PARAMETERS_PATHPrimer3 File - http://primer3.sourceforge.netFirst line must be "Primer3 File - http://primer3.sourceforge.net" in Incorrect file format (too few lines) in Unknown file type in at line 2 (line2='Unexpected P3 file type parsedIllegal value: Too many elements for tag PRIMER_PRODUCT_SIZE_RANGEToo many values for PRIMER_P3_FILE_IDInput line with no '=': SEQUENCEDuplicate tag: PRIMER_SEQUENCE_IDMARKER_NAMEPRIMER_LEFT_INPUTPRIMER_RIGHT_INPUTPRIMER_INTERNAL_OLIGO_INPUTPRIMER_START_CODON_POSITIONPRIMER_DEFAULT_PRODUCTPRIMER_DEFAULT_SIZEPRIMER_OPT_SIZEPRIMER_MIN_SIZEPRIMER_MAX_SIZEPRIMER_MAX_POLY_XPRIMER_OPT_TMPRIMER_OPT_GC_PERCENTPRIMER_MIN_TMPRIMER_MAX_TMPRIMER_MAX_DIFF_TMPRIMER_TM_SANTALUCIAPRIMER_SALT_CORRECTIONSPRIMER_MIN_GCPRIMER_MAX_GCPRIMER_SALT_CONCPRIMER_DIVALENT_CONCPRIMER_DNTP_CONCPRIMER_DNA_CONCPRIMER_NUM_NS_ACCEPTEDPRIMER_PRODUCT_OPT_SIZEPRIMER_SELF_ANYPRIMER_SELF_ENDPRIMER_PAIR_ANYPRIMER_PAIR_ENDPRIMER_FILE_FLAGPRIMER_PICK_ANYWAYPRIMER_GC_CLAMPPRIMER_EXPLAIN_FLAGPRIMER_LIBERAL_BASEPRIMER_FIRST_BASE_INDEXPRIMER_NUM_RETURNPRIMER_MIN_QUALITYPRIMER_MIN_END_QUALITYPRIMER_QUALITY_RANGE_MINPRIMER_QUALITY_RANGE_MAXPRIMER_PRODUCT_MAX_TMPRIMER_PRODUCT_MIN_TMPRIMER_PRODUCT_OPT_TMPRIMER_SEQUENCING_LEADPRIMER_SEQUENCING_SPACINGPRIMER_SEQUENCING_INTERVALPRIMER_SEQUENCING_ACCURACYPRIMER_PICK_INTERNAL_OLIGOPRIMER_INTERNAL_OLIGO_OPT_TMPRIMER_INTERNAL_OLIGO_MAX_TMPRIMER_INTERNAL_OLIGO_MIN_TMPRIMER_INTERNAL_OLIGO_MIN_GCPRIMER_INTERNAL_OLIGO_MAX_GCPRIMER_INTERNAL_OLIGO_NUM_NSPRIMER_MAX_MISPRIMINGPRIMER_PAIR_MAX_MISPRIMINGPRIMER_INSIDE_PENALTYPRIMER_OUTSIDE_PENALTYPRIMER_MAX_END_STABILITYPRIMER_LOWERCASE_MASKINGPRIMER_WT_TM_GTPRIMER_WT_TM_LTPRIMER_WT_GC_PERCENT_GTPRIMER_WT_GC_PERCENT_LTPRIMER_WT_SIZE_LTPRIMER_WT_SIZE_GTPRIMER_WT_COMPL_ANYPRIMER_WT_COMPL_ENDPRIMER_WT_NUM_NSPRIMER_WT_REP_SIMPRIMER_WT_SEQ_QUALPRIMER_WT_END_QUALPRIMER_WT_POS_PENALTYPRIMER_WT_END_STABILITYPRIMER_WT_TEMPLATE_MISPRIMINGPRIMER_IO_WT_TM_GTPRIMER_IO_WT_TM_LTPRIMER_IO_WT_GC_PERCENT_GTPRIMER_IO_WT_GC_PERCENT_LTPRIMER_IO_WT_SIZE_LTPRIMER_IO_WT_SIZE_GTPRIMER_IO_WT_COMPL_ANYPRIMER_IO_WT_COMPL_ENDPRIMER_IO_WT_NUM_NSPRIMER_IO_WT_REP_SIMPRIMER_IO_WT_SEQ_QUALPRIMER_IO_WT_END_QUALPRIMER_PAIR_WT_PR_PENALTYPRIMER_PAIR_WT_IO_PENALTYPRIMER_PAIR_WT_DIFF_TMPRIMER_PAIR_WT_COMPL_ANYPRIMER_PAIR_WT_COMPL_ENDPRIMER_PAIR_WT_PRODUCT_TM_LTPRIMER_PAIR_WT_PRODUCT_TM_GTPRIMER_PAIR_WT_REP_SIMSEQUENCE_TEMPLATESEQUENCE_PRIMERSEQUENCE_PRIMER_REVCOMPSEQUENCE_INTERNAL_OLIGOInvalid range at tag SEQUENCE_TARGETSEQUENCE_EXCLUDED_REGIONSEQUENCE_INCLUDED_REGIONSEQUENCE_START_CODON_POSITIONSEQUENCE_FORCE_LEFT_STARTSEQUENCE_FORCE_LEFT_ENDSEQUENCE_FORCE_RIGHT_STARTSEQUENCE_FORCE_RIGHT_ENDPRIMER_PAIR_MAX_DIFF_TMPRIMER_TM_FORMULAPRIMER_SALT_MONOVALENTPRIMER_SALT_DIVALENTPRIMER_MAX_NS_ACCEPTEDPRIMER_MAX_SELF_ANYPRIMER_MAX_SELF_ENDPRIMER_MAX_SELF_ANY_THPRIMER_MAX_SELF_END_THPRIMER_MAX_HAIRPIN_THPRIMER_PAIR_MAX_COMPL_ANYPRIMER_PAIR_MAX_COMPL_ENDPRIMER_PAIR_MAX_COMPL_ANY_THPRIMER_PAIR_MAX_COMPL_END_THP3_FILE_FLAGPRIMER_MAX_END_GCPRIMER_PICK_RIGHT_PRIMERPRIMER_PICK_LEFT_PRIMERPRIMER_INTERNAL_OPT_SIZEPRIMER_INTERNAL_MAX_SIZEPRIMER_INTERNAL_MIN_SIZEPRIMER_INTERNAL_MAX_POLY_XPRIMER_INTERNAL_OPT_TMPRIMER_INTERNAL_MAX_TMPRIMER_INTERNAL_MIN_TMPRIMER_INTERNAL_MIN_GCPRIMER_INTERNAL_MAX_GCPRIMER_INTERNAL_SALT_DIVALENTPRIMER_INTERNAL_DNTP_CONCPRIMER_INTERNAL_DNA_CONCPRIMER_INTERNAL_MIN_QUALITYPRIMER_INTERNAL_MAX_SELF_ANYPRIMER_INTERNAL_MAX_SELF_ENDPRIMER_MAX_LIBRARY_MISPRIMINGPRIMER_WT_SELF_ANYPRIMER_WT_SELF_ENDPRIMER_WT_SELF_ANY_THPRIMER_WT_SELF_END_THPRIMER_WT_HAIRPIN_THPRIMER_WT_LIBRARY_MISPRIMINGPRIMER_INTERNAL_WT_TM_GTPRIMER_INTERNAL_WT_TM_LTPRIMER_INTERNAL_WT_SIZE_LTPRIMER_INTERNAL_WT_SIZE_GTPRIMER_INTERNAL_WT_SELF_ANYPRIMER_INTERNAL_WT_SELF_ENDPRIMER_INTERNAL_WT_HAIRPIN_THPRIMER_INTERNAL_WT_NUM_NSPRIMER_INTERNAL_WT_SEQ_QUALPRIMER_INTERNAL_WT_END_QUALPRIMER_PAIR_WT_COMPL_ANY_THPRIMER_PAIR_WT_COMPL_END_THUnrecognized tag: Unrecognized tag: %s pick_pcr_primerspick_left_onlypick_right_onlypick_hyb_probe_onlyUnrecognized PRIMER_TASKgenericpick_detection_primerspick_cloning_primerspick_discriminative_primerspick_sequencing_primerspick_primer_listcheck_primersmispriming libraryinternal oligo mishyb librarypa->pick_internal_oligoread_boulder.cPRIMER_SEQUENCE_QUALITYPRIMER_MISPRIMING_LIBRARYPRIMER_COMMENTP3_COMMENT__null != file_nameCannot open Settings file is empty: P3_FILE_TYPE=all_parametersP3_FILE_TYPE=sequenceP3_FILE_TYPE=settings') in P3_SETTINGS_FILE_USED=%s Line 3 must be empty in P3_SETTINGS_FILE_END=TMPECPRIMER_WARNING=%s fflush(stdout) failedPRIMER_ERROR=%s = __null != paprint_boulder.cINTERNALPRIMER_LEFT_EXPLAIN=%s PRIMER_RIGHT_EXPLAIN=%s OLIGO_PRIMER_INTERNAL_%sEXPLAIN=%s PRIMER_PAIR_EXPLAIN=%s PRIMER_LEFT_NUM_RETURNED=%d PRIMER_RIGHT_NUM_RETURNED=%d PRIMER_%s_NUM_RETURNED=%d PRIMER_PAIR_NUM_RETURNED=%d _%dPRIMER_PAIR_PENALTY%s=%.4f PRIMER_PAIR%s_PENALTY=%f PRIMER_LEFT%s_PENALTY=%f PRIMER_RIGHT%s_PENALTY=%f PRIMER_%s%s_PENALTY=%f PRIMER_LEFT%s_PROBLEMS=%s PRIMER_RIGHT%s_PROBLEMS=%s PRIMER_%s%s_PROBLEMS=%s PRIMER_LEFT%s_SEQUENCE=%s PRIMER_RIGHT%s_SEQUENCE=%s PRIMER_%s%s_SEQUENCE=%s PRIMER_LEFT%s=%d,%d PRIMER_RIGHT%s=%d,%d PRIMER_%s%s=%d,%d PRIMER_LEFT%s_TM=%.3f PRIMER_RIGHT%s_TM=%.3f PRIMER_%s%s_TM=%.3f PRIMER_%s%s_GC_PERCENT=%.3f PRIMER_LEFT%s_SELF_ANY=%.2f PRIMER_RIGHT%s_SELF_ANY=%.2f PRIMER_%s%s_SELF_ANY=%.2f PRIMER_%s%s_SELF_ANY_TH=%.2f PRIMER_LEFT%s_SELF_END=%.2f PRIMER_RIGHT%s_SELF_END=%.2f PRIMER_%s%s_SELF_END=%.2f PRIMER_%s%s_SELF_END_TH=%.2f PRIMER_%s%s_HAIRPIN_TH=%.2f PRIMER_PAIR%s_COMPL_ANY=%.2f PRIMER_PAIR%s_COMPL_END=%.2f PRIMER_PRODUCT_SIZE%s=%d PRIMER_PRODUCT_TM%s=%.4f PRIMER_PAIR%s_T_OPT_A=%.4f PRIMER_STOP_CODON_POSITION=%d PRIMER_LEFT%s_GC_PERCENT=%.3f PRIMER_RIGHT%s_GC_PERCENT=%.3f PRIMER_LEFT%s_SELF_ANY_TH=%.2f PRIMER_RIGHT%s_SELF_ANY_TH=%.2f PRIMER_LEFT%s_SELF_END_TH=%.2f PRIMER_RIGHT%s_SELF_END_TH=%.2f PRIMER_LEFT%s_HAIRPIN_TH=%.2f PRIMER_RIGHT%s_HAIRPIN_TH=%.2f PRIMER_LEFT%s_MISPRIMING_SCORE=%.2f, %s PRIMER_RIGHT%s_MISPRIMING_SCORE=%.2f, %s PRIMER_PAIR%s_MISPRIMING_SCORE=%.2f, %s PRIMER_%s%s_MISHYB_SCORE=%.2f, %s PRIMER_LEFT%s_LIBRARY_MISPRIMING=%.2f, %s PRIMER_RIGHT%s_LIBRARY_MISPRIMING=%.2f, %s PRIMER_PAIR%s_LIBRARY_MISPRIMING=%.2f, %s PRIMER_%s%s_LIBRARY_MISHYB=%.2f, %s PRIMER_LEFT%s_MIN_SEQ_QUALITY=%d PRIMER_RIGHT%s_MIN_SEQ_QUALITY=%d PRIMER_%s%s_MIN_SEQ_QUALITY=%d PRIMER_LEFT%s_POSITION_PENALTY=%f PRIMER_RIGHT%s_POSITION_PENALTY=%f PRIMER_LEFT%s_END_STABILITY=%.4f PRIMER_RIGHT%s_END_STABILITY=%.4f PRIMER_LEFT%s_TEMPLATE_MISPRIMING=%.4f PRIMER_RIGHT%s_TEMPLATE_MISPRIMING=%.4f PRIMER_LEFT%s_TEMPLATE_MISPRIMING_TH=%.4f PRIMER_RIGHT%s_TEMPLATE_MISPRIMING_TH=%.4f PRIMER_PAIR%s_COMPL_ANY_TH=%.2f PRIMER_PAIR%s_COMPL_END_TH=%.2f PRIMER_PRODUCT_TM_OLIGO_TM_DIFF%s=%.4f PRIMER_PAIR%s_PRODUCT_SIZE=%d PRIMER_PAIR%s_PRODUCT_TM=%.4f PRIMER_PAIR%s_PRODUCT_TM_OLIGO_TM_DIFF=%.4f PRIMER_PAIR%s_TEMPLATE_MISPRIMING=%.2f PRIMER_PAIR%s_TEMPLATE_MISPRIMING_TH=%.2f )CAApA`AAAPA@AAA0AA AAAAAAA8A8AAAAAAAAAAAAAAAAAAAxAAApAAhA`AAAAXAPAAA@AHAAA AG A AG AG AG A AG AG AG AG AG AG A AG AG AG AG AG A AG AG AG AG AG AG AG AG AG AG AG AG A AG A AG AG AG A AG AG AG AG AG AG A AG AG AG AG AG A AE AW A= AW AW AW A5 AW AW A- AW A% AW AW AW AW A A AW AW A A AW A AW AW AW AW AW AW AW AW AE AW A= AW AW AW A5 AW AW A- AW A% AW AW AW AW A A AW AW A A AW A AC5a 0`   0 ` Y0`libprimer3 release 2.3.3=============BEGIN GLOBAL ARGS primer_task %i pick_left_primer %i pick_right_primer %i pick_internal_oligo %i file_flag %i first_base_index %i liberal_base %i num_return %i pick_anyway %i quality_range_min %i quality_range_max %i tm_santalucia %i salt_corrections %i max_end_stability %f gc_clamp %i max_end_gc %i lowercase_masking %i thermodynamic_alignment %i outside_penalty %f inside_penalty %f product size ranges: %d - %d product_opt_size %i product_max_tm %f product_min_tm %f product_opt_tm %f pair_repeat_compl %f pair_compl_any %f pair_compl_end %f pair_compl_any_th %f pair_compl_end_th %f dump %i begin pr_pair_weights primer_quality %f io_quality %f diff_tm %f compl_any %f compl_end %f compl_any_th %f compl_end_th %f product_tm_lt %f product_tm_gt %f product_size_lt %f product_size_gt %f repeat_sim %f template_mispriming %f end pair_weightsBEGIN primer_argsbegin oligo_weightstemplate_mispriming_th %f end oligo_weightsmax_self_any_th %f max_self_end_th %f max_hairpin %f max_template_mispriming %f end primer args temp_gt %f temp_lt %f gc_content_gt %f gc_content_lt %f hairpin %f length_lt %f length_gt %f seq_quality %f end_quality %f pos_penalty %f end_stability %f num_ns %f end internal oligo_weights opt_tm %f min_tm %f max_tm %f opt_gc_content %f max_gc %f min_gc %f divalent_conc %f dntp_conc %f dna_conc %f num_ns_accepted %i opt_size %i min_size %i max_size %i max_poly_x %i min_end_quality %i min_quality %i max_self_any %f max_self_end %f max_repeat_compl %f end internal oligo argsEND GLOBAL ARGSBEGIN SEQUENCE ARGS %i incl_s %i incl_l %i start_codon_pos %i quality_storage_size %i *sequence %s *sequence_name %s *sequence_file %s *trimmed_seq %s *trimmed_orig_seq %s *upcased_seq %s *upcased_seq_r %s *left_input %s *right_input %s *internal_input %s force_left_start %i force_left_end %i force_right_start %i force_right_end %i END SEQUENCE ARGS__null != xlibprimer3.c1 == sa->tar2.count__null != ostart >= 0start + o->length <= seq_len__null != oligoLEFT PRIMERSINTERNAL OLIGOSRIGHT PRIMERSACCEPTABLE %s # self self lib qual- N GC%% Tm any_th end_th pin any end sim lity %5.2fh->repeat_sim.score != __null %6.3f s != __nulllen >= 3start <= (len - 3)__null != s__null != sep; (for internal oligo) illegal intervalNegative Too short/Too longToo many NsOverlaps TargetOverlaps Excluded RegionUnacceptable GC contentNo GC clampTm too lowTm too highHigh self complementarityHigh end self complementarityLong poly-XLow sequence qualityHigh 3' stabilityWould not amplify any ORFNot in any ok left regionNot in any ok right regionMasked with lowercase letter is unacceptable: ssz <= 2147483647Unable to open file for writingconsidered %d, too many Ns %d, overlap target %d, overlap excluded region %d, GC content failed %d, GC clamp failed %d, low tm %d, high tm %d, high any compl %d, high end compl %d, high hairpin stability %d, high repeat similarity %d, long poly-x seq %d, low sequence quality %d, high 3' stability %d, ok %d, no target %d, low product Tm %d, high product Tm %d, tm diff too large %d, no internal oligo %d, not in any ok region %dr.score <= 32767r.score != (-2147483647 - 1)h != __nullk >= 0k < ((sa)->incl_l)!p3_ol_is_ok(h) - temporaryNo primers providedMissing SEQUENCE tagPRIMER_PAIR_OK_REGION_LIST%s beyond end of sequenceNegative %s length%s outside of INCLUDED_REGIONvector::reservevector::_M_fill_inserth->template_mispriming >= 0.0sum >= 0.0Sequence quality data missingPRIMER_MIN_SIZE must be >= 136PRIMER_NUM_RETURN < 1probably primer3_core lib_ambiguity_codes_consensus %i number of product size ranges: %d pair_max_template_mispriming %f pair_max_template_mispriming_th %f min_left_three_prime_distance %i min_right_three_prime_distance %i min_5_prime_overlap_of_junction %i min_3_prime_overlap_of_junction %i template_mispriming_th %f max_template_mispriming_th %f begin internal oligo args (p->o_args.) begin internal oligo_weights (p->o_args.weights.)primer_overlap_junctions_count %i primer_overlap_junctions_list [OT_LEFT == o_type || OT_RIGHT == o_type!(bf_get_infinite_pos_penalty(h))oligo_max_template_mispriming(h) != -1.7976931348623157e+308oligo_max_template_mispriming_thermod(h) != -1.7976931348623157e+308oligo->start + sa->incl_s >= 0oligo->start + sa->incl_s + oligo->length <= seq_len %4d-based # self self hair- # sequence start ln %4d %-30s %5d %2d %2d %5.2f %5.3f %5.2f %5.2fdirection == 1 || direction == -1internal oligio mishyb libraryHigh hairpin stability (thermod. approach)High similarity to mispriming or mishyb libraryInternal error, not enough space for "explain" string, would not amplify any of the ORF %d, high template mispriming score %d, lowercase masking of 3' end %d, not in any ok left region %d, not in any ok right region %d, unacceptable product size %d, high mispriming library similarity %d, no overlap of required point %d, primer in pair overlaps a primer in a better pair %d, left primer to right of right primer %dr.temp <= 1.7976931348623157e+308OT_LEFT == l || OT_RIGHT == l || OT_INTL == lsa->tar2.count <= 1 || (-1.0 == pa->inside_penalty && 0.0 == pa->outside_penalty)2147483647 > (n=strlen(sa->trimmed_seq))No right primer found in range No left primer found in range Calculation error in forward sequencing position calculationCalculation error in reverse sequencing position calculationIncrease PRIMER_NUM_RETURN to obtain all sequencing primersCalculation error in forced primer position calculationMore than one position in template for input oligo ppair->right->start - ppair->left->start + 1 > 0ppair->product_tm != -999999.9999ppair->left->template_mispriming != -1.7976931348623157e+308ppair->left->template_mispriming_r != -1.7976931348623157e+308ppair->right->template_mispriming != -1.7976931348623157e+308ppair->right->template_mispriming_r != -1.7976931348623157e+308dpal_set_ambiguity_code_matrix(h->local_ambig)dpal_set_ambiguity_code_matrix(h->local_end_ambig)Task pick_sequencing_primers cannot be combined with included regionTask pick_discriminative_primers requires exactly one SEQUENCE_TARGETpa->pr_pair_weights.template_mispriming >= 0.0pa->pr_pair_weights.template_mispriming_th >= 0.0Minimum 3' distance must be >= -1 (min_*_three_prime_distance)Value too small at tag PRIMER_FIRST_BASE_INDEXValue too large at tag PRIMER_PAIR_MAX_TEMPLATE_MISPRIMINGValue too large at tag PRIMER_MAX_TEMPLATE_MISPRIMINGValue too large at tag PRIMER_MAX_LIBRARY_MISPRIMINGValue too large at tag PRIMER_INTERNAL_MAX_LIBRARY_MISHYBValue too large at tag PRIMER_PAIR_MAX_LIBRARY_MISPRIMINGPRIMER_INTERNAL_MAX_TEMPLATE_MISHYB is not supportedPRIMER_INTERNAL_MAX_TEMPLATE_MISHYB_TH is not supportedPRIMER_MAX_SIZE exceeds built-in maximum of PRIMER_{OPT,DEFAULT}_SIZE > PRIMER_MAX_SIZEPRIMER_{OPT,DEFAULT}_SIZE < PRIMER_MIN_SIZEPRIMER_INTERNAL_MAX_SIZE exceeds built-in maximumPRIMER_INTERNAL_{OPT,DEFAULT}_SIZE > MAX_SIZEPRIMER_INTERNAL_{OPT,DEFAULT}_SIZE < MIN_SIZEPRIMER_GC_CLAMP > PRIMER_MIN_SIZEPRIMER_MAX_END_GC must be between 0 to 5Empty value for PRIMER_PRODUCT_SIZE_RANGEIllegal element in PRIMER_PRODUCT_SIZE_RANGEPRIMER_MAX_SIZE > min PRIMER_PRODUCT_SIZE_RANGEPRIMER_INTERNAL_MAX_SIZE > min PRIMER_PRODUCT_SIZE_RANGEValue for SEQUENCE_INCLUDED_REGION too largeIllegal value for SEQUENCE_INCLUDED_REGIONSEQUENCE_INCLUDED_REGION length < min PRIMER_PRODUCT_SIZE_RANGEPRIMER_MAX_END_STABILITY must be non-negativeCannot accept both SEQUENCE_START_CODON_POSITION and non-default arguments for PRIMER_INSIDE_PENALTY or PRIMER_OUTSIDE_PENALTYStart codon position not contained in SEQUENCE_INCLUDED_REGIONNo start codon at SEQUENCE_START_CODON_POSITIONPRIMER_MIN_QUALITY < PRIMER_QUALITY_RANGE_MINPRIMER_MIN_QUALITY > PRIMER_QUALITY_RANGE_MAXPRIMER_INTERNAL_MIN_QUALITY < PRIMER_QUALITY_RANGE_MINPRIMER_INTERNAL_MIN_QUALITY > PRIMER_QUALITY_RANGE_MAXSequence quality score out of rangeSequence quality is part of objective function but sequence quality is not definedUnrecognized base in input sequenceOptimum primer Tm lower than minimum or higher than maximumOptimum internal oligo Tm lower than minimum or higher than maximumIllegal value for PRIMER_MAX_GC and PRIMER_MIN_GCIllegal value for PRIMER_INTERNAL_OLIGO_GCIllegal value for PRIMER_MAX_NS_ACCEPTEDIllegal value for PRIMER_INTERNAL_MAX_NS_ACCEPTEDIllegal value for primer complementarity restrictionsIllegal value for primer complementarity restrictions (thermod. approach)Illegal value for internal oligo complementarity restrictionsIllegal value for primer salt or dna concentrationIllegal value for primer divalent salt or dNTP concentrationIllegal value for internal oligo salt or dna concentrationIllegal value for internal oligo divalent salt or dNTP concentrationNon-default inside penalty or outside penalty is valid only when number of targets <= 1has no effect when number of targets is 0Not specified to pick internal oligos but a specific internal oligo is providedSpecified internal oligo exceeds built-in maximum of Specified internal oligo > PRIMER_INTERNAL_MAX_SIZESpecified internal oligo < PRIMER_INTERNAL_MIN_SIZESpecified internal oligo not in sequenceSpecified internal oligo not in Included RegionSpecified left primer exceeds built-in maximum of Specified left primer > PRIMER_MAX_SIZESpecified left primer < PRIMER_MIN_SIZESpecified left primer not in sequenceSpecified left primer not in Included RegionSpecified right primer exceeds built-in maximum of Specified right primer < PRIMER_MIN_SIZESpecified right primer > PRIMER_MAX_SIZESpecified right primer not in sequenceSpecified right primer not in Included RegionProduct temperature is part of objective function while optimum temperature is not definedProduct size is part of objective function while optimum size is not definedPrimer GC content is part of objective function while optimum gc_content is not definedHyb probe GC content is part of objective function while optimum gc_content is not definedInternal oligo quality is part of objective function while internal oligo choice is not requiredMispriming score is part of objective function, but mispriming library is not definedInternal oligo mispriming score is part of objective function while mishyb library is not definedIllegal value for PRIMER_SEQUENCING_LEADIllegal value for PRIMER_SEQUENCING_INTERVALIllegal value for PRIMER_SEQUENCING_ACCURACYIllegal value for PRIMER_SEQUENCING_SPACINGPRIMER_SEQUENCING_INTERVAL > PRIMER_SEQUENCING_SPACINGPRIMER_SEQUENCING_ACCURACY > PRIMER_SEQUENCING_SPACINGPRIMER_SEQUENCING_LEAD > PRIMER_SEQUENCING_SPACINGSEQUENCE_FORCE_LEFT_START > SEQUENCE_FORCE_LEFT_ENDSEQUENCE_FORCE_RIGHT_END > SEQUENCE_FORCE_RIGHT_STARTIllegal value for PRIMER_MIN_5_PRIME_OVERLAP_OF_JUNCTIONIllegal value for PRIMER_MIN_3_PRIME_OVERLAP_OF_JUNCTIONPRIMER_MIN_5_PRIME_OVERLAP_OF_JUNCTION > PRIMER_MAX_SIZE / 2PRIMER_MIN_3_PRIME_OVERLAP_OF_JUNCTION > PRIMER_MAX_SIZE / 2PRIMER_SALT_DIVALENT > 0.0 but PRIMER_DNTP_CONC <= 0.0; use reasonable value for PRIMER_DNTP_CONC Copyright (c) 1996,1997,1998,1999,2000,2001,2004,2006,2007,2008 2009,2010,2011,2012 Whitehead Institute for Biomedical Research, Steve Rozen (http://purl.com/STEVEROZEN/), Andreas Untergasser and Helen Skaletsky All rights reserved. This file is part of the primer3 suite and libraries. The primer3 suite and libraries are free software; you can redistribute them and/or modify them under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version. This software is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. You should have received a copy of the GNU General Public License along with this software (file gpl-2.0.txt in the source distribution); if not, write to the Free Software Foundation, Inc., 51 Franklin St, Fifth Floor, Boston, MA 02110-1301 USA THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT OWNERS OR CONTRIBUTORS BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE. ?4@Y@@>@?.333333?ffffff?-@ư>Illegal weightEmpty sequence in Unrecognized character (, entry Empty B BAA BAAAAAAAAAAAAAAAAAA BAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAB8BB8BAAB8BAA8BA8BAAAA8B8BBA8B8BA8BAAAAAAAB8BB8BAAB8BAA8BA8BAAAA8B8BBA8B8BA8BMissing id line (expected '>') in BDHVRYKMSWNACGTAGTACTACGACATOut of memoryNULL first sequenceNULL second sequenceNULL 'in' pointerIllegal flagEmpty first sequenceEmpty second sequenceFirst sequence too long for _dpal_genericSecond sequence too long for _dpal_genericscore_only must be 0 if debug is non-0Sequence 1 longer than DPAL_MAX_ALIGN and alignment is requestedSequence 2 longer than DPAL_MAX_ALIGN and alignment is requested_dpal_long_nopath_maxgap1_local requires ylen >= 3 _dpal_long_nopath_maxgap1_local_end requires ylen >= 3 SEQ STR Illegal type0 dS = %g dH = %g inf inf STR %s Unable to open file %sinf%lf%lgstack.dsstackmm.dsstackmm.dhdangle.dsdangle.dhloops.dsloops.dhtstack_tm_inf.dststack.dhtstack2.dststack2.dhtriloop.dstriloop.dhtetraloop.dstetraloop.dhNo predicted secondary structures for given sequencesCalculated thermodynamical parameters for dimer: dS = %g dH = %g dG = %g t = %g Sequences longer than THAL_MAX_ALIGN for thermodynamical alignment (nearest-neighbor approach)Sequence 1 longer than THAL_MAX_SEQ and alignment is requestedSequence 2 longer than THAL_MAX_SEQ and alignment is requestedNo predicted sec struc for given seq Calculated thermodynamical parameters for dimer: %d dS = %g dH = %g dG = %g t = %g No secondary structure could be calculated fffffq@dh㈵>fffffq@eAz):?^@@@Zd;O?eA0@`T@D@Yn?dy=)\(?)\(@@)>4vxU?uR#>@!?@I +ֿ`"?>pX9v?T[r@Pnпv?/$u?;l l~ p ` ( Ќ@ 0h  8 ` p H00P0pP XhPQpT8TXUxl lPlPm `m8pmPmhmmmmnoppq(q@qXqpqqqrr r0rPr0`rHpr`rxrrr sPs`sps s8sPshssssstt t(0t@@tXPtp`tpttttttt0tHt`uxu u0u@uPu`upu u8uPuhuuuuuvv v(0v@@vXPvp`vpvvvvvvv0vHv`wxw w0w@wPw`wpw w8wPwhwwwwwxx x(0x@@xXPxp`xpxxxxxxx0xHx`yxy y0y@yPy`ypy y8yPyhyyyyyzz z( 0z@ @zX Pzp `z pz z z z z!z!z0!zH!z`!{x!{! {!0{!@{!P{!`{"p{ "{8"{P"{h"{"{"{"{"{"|"|# |(#0|@#@|X#P|p#`|#p|#|#|#|#|$|$}0$}H$ }`$0}x$@}$`$% %H%h%@%`%P%`&PH&`&&' 0'PP'h''`'''@(0@(``(((ЪP)0p))))))Ы*0* P***а*p*в(+H+`h+++ + ,8,h,,,,-(-P--p-0-0(.P...P /P/ // 00P012@82PX2x22%83B3_`1`2a3d3 d30d4e840eX4`ex4e4e4@i85@j`5j50o5p5Pr6r86px6y6y60777P78`(8@8X8 p88М888899`9(:@x:::0;@`;;`;;; @< `< <<@Q8=R`=0S=S=UH> W>l? m8?@n`?r?ps?t?@8@P@zPRxX@ $$xr]AGw AH LsAD@FLlt9 BIB B(A0C8J 8C0A(B BBBF p+A$_N z H N$_N z H N$G\<0BEE B(D0D8F@O 8I0A(B BBBK D8A0A(B BBB,p M[P" F b F $PMI  N z,(`M` I L$XwBOE H(D0G8G 8D0A(B BBBN dtBBB E(D0D8GJ 8A0A(B BBBA  8F0A(B BBB\/BEE B(A0D8GP 8F0A(B BBBI t8A0A(B BBBL<RBBE E(A0D8G 8A0A(B BBBH )DDM G DDM G D/MD \^ML @d$BEB E(D0D8J` 8A0A(B BBBB e 8C0A(B BBBA \PBED I(J@N (A ABBF V (A ABBD _ (A ABBA LBBA D(J@ (C ABBD J(A ABBL<@BEB B(D0D8DP 8A0A(B BBBA ,D N F SLBED D(J@} (A ABBD V (A ABBA L BED A(G0A (A ABBA i (D ABBK LLЪBEB B(A0C8J  8A0A(B BBBE ,@?MMQf G 0BBD d A `BBD d A L BBEB B(D0D8Gl 8A0A(B BBBH \@Yt8Y($PYH I N B (Z ZZZZ,Z DY \Y<tZ[X\`]X]P] H] @]4 8]L 0]d (]| ] ] ] ] ] ]  ]*$ ]< ](T (]/l @]/ X]  P] H] @]  8]  0] (], ]D ]\ ] t ]  ]  \  \  \ \ \  \ 4 \ L \ d \ | \  \ \ \  \  \  \ $ x\ < p\T h\l `\ X\ P\ H\ @\ 8\ 0\(\, \ D\ \\ t\\[[[[[[ 4[ L[ d[ |[ [ [ [ [ [  [$x[<p[ Th[ l`[ X[ P[ H[ @[ 8[ 0[ ([ , [D[ \[ t[ [ZZ Z ZZZ 4Z LZdZ|ZZZZ Z Z  Z$xZ <pZThZ l`Z XZ PZ HZ @Z 8Z 0Z (Z , Z DZ \Z tZ Z Y Y Y Y Y Y 4Y LY dY |Y Y Y Y Y Y  Y $xY <pYThYl`YXY PYHY@Y 8Y 0Y (Y , Y DY \Y tY Y XXXXX X4XLX dX/|XXXXXX XL$XBED A(D0 (F ABBE D(A ABBtxgTD_ A gJDU A $gfD  B ` H 0i DQ K r!DS E 4rBHD  AGA DAD$TtHN x B z F ,|`vBDD  AGA ,@wBDD z ABA dx BEE B(D0A8L` 8C0A(B BBBE \ 8F0A(B BBBE <DzvBDC H AGG  ABH {AX{AU{"DN A {&Da|"DN A $ |MI ~ D D|Ay F $d}MN0e H ~!DM A $ ~MI N D X H ~!DM A ~UDQ K D A 48BDA G0  AABE LBBB B(D0D8FPp 8F0A(B BBBK  8F0A(B BBBI e 8F0A(B BBBD l8C0A(B BBBxWDQ K F A $KADG |AA, D؁ \Ё tȁ  DW"DN N A4ȁBDD G09  AABB $0MV0f G DAZdD G A4xUBDA 9 ABM AAB:Dl H ABDu G AEDr J D< 6BAD  EEK K AEA $\ /S`A D , (BHA N ABD  , BHA  ABD   !cAaD4!X~B`t L(K0K80A(B BBB|! 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