Biochemical Properties


Protein Name: TOP6A_HALS3 RecName: Full=Type 2 DNA topoisomerase 6 subunit A; AltName: Full=Type II DNA topoisomerase VI subunit A

Strain: Haloferax volcanii


Number of amino acids: 366

Molecular weight: 41448.5

Theoretical pI: 4.34

Total number of negatively charged residues (Asp + Glu): 74

Total number of positively charged residues (Arg + Lys): 36

Instability index:The instability index (II) is computed to be 42.93

This classifies the protein as unstable

Aliphatic index: 77.27

Grand average of hydropathicity (GRAVY): -0.651

Amino acid composition (%):

Ala Arg Asn Asp Cys Gln Glu Gly His Ile Leu lys Mcf Phe Pro Ser Thr Trp Tyr Val
6.6 7.1 2.2 11.7 0.5 5.7 8.5 6.3 1.6 4.1 9.6 2.7 1.6 3.6 4.1 7.7 5.5 1.1 3.8 6.0


Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 Hours (Mammalian reticulocytes, in vitro)

Atom composition:
Carbon Hydrogen Nitrogen Oxygen Sulphur
1806 2793 499 606 8