Biochemical Properties


Protein Name: TPMT_AZOVD RecName: Full Thiopurine S-methyltransferase; AltName: Full Thiopurine methyltransferase

Strain: Azotobacter Vinelandii


Number of amino acids: 218

Molecular weight: 24924.5

Theoretical pI: 5.98

Total number of negatively charged residues (Asp + Glu): 31

Total number of positively charged residues (Arg + Lys): 28

Instability index:The instability index (II) is computed to be 35.36

This classifies the protein as stable

Aliphatic index: 94.86

Grand average of hydropathicity (GRAVY): -0.202

Amino acid composition (%):

Ala Arg Asn Asp Cys Gln Glu Gly His Ile Leu lys Mcf Phe Pro Ser Thr Trp Tyr Val
11.0 5.5 3.4 3.9 0.0 6.4 12.6 6.2 0.2 3.9 8.7 6.4 1.6 3.9 4.1 5.3 3.4 0.2 2.3 10.8


Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 Hours (Mammalian reticulocytes, in vitro)

Atom composition:
Carbon Hydrogen Nitrogen Oxygen Sulphur
1116 1736 324 311 8