Biochemical Properties


Protein Name: 5-formyltetrahydrofolate cyclo-ligase

Strain: Salinibacter ruber M8


Number of amino acids: 236

Molecular weight: 25691.0

Theoretical pI: 5.20

Total number of negatively charged residues (Asp + Glu): 37

Total number of positively charged residues (Arg + Lys): 28

Instability index:The instability index (II) is computed to be 47.12

This classifies the protein as unstable

Aliphatic index: 81.48

Grand average of hydropathicity (GRAVY): -0.365

Amino acid composition (%):

Ala Arg Asn Asp Cys Gln Glu Gly His Ile Leu lys Mcf Phe Pro Ser Thr Trp Tyr Val
11.9 9.3 0.8 8.5 0.8 1.3 7.2 6.8 2.5 3.8 8.1 2.5 1.3 3.4 11.9 3.8 5.9 1.3 0.8 8.1


Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 Hours (Mammalian reticulocytes, in vitro)

Atom composition:
Carbon Hydrogen Nitrogen Oxygen Sulphur
1138 1798 328 341 5