Biochemical Properties


Protein Name: LEU3_CHRSD RecName: Full=3-isopropylmalate dehydrogenase; AltName: Full=3-IPM-DH; AltName: Full=Beta-IPM dehydrogenase; Short=IMDH

Strain: Chromohalobacter salexigens DSM 3043


Number of amino acids: 359

Molecular weight: 38363.0

Theoretical pI: 4.88

Total number of negatively charged residues (Asp + Glu): 47

Total number of positively charged residues (Arg + Lys): 33

Instability index:The instability index (II) is computed to be 36.10

This classifies the protein as stable

Aliphatic index: 100.92

Grand average of hydropathicity (GRAVY): 0.030

Amino acid composition (%):

Ala Arg Asn Asp Cys Gln Glu Gly His Ile Leu lys Mcf Phe Pro Ser Thr Trp Tyr Val
12.8 6.1 2.8 5.0 0.8 3.6 8.1 10.3 1.1 6.7 11.1 3.1 3.6 1.9 5.3 4.7 3.3 0.6 2.5 6.4


Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 Hours (Mammalian reticulocytes, in vitro)

Atom composition:
Carbon Hydrogen Nitrogen Oxygen Sulphur
1689 2733 469 515 16