Biochemical Properties

Protein Name: THIC_HALSA RecName: Full=Phosphomethylpyrimidine synthase; AltName: Full=Hydroxymethylpyrimidine phosphate synthase; Short=HMP-P synthase; Short=HMP-phosphate synthase; Short=HMPP synthase; AltName: Full=Thiamine biosynthesis protein ThiC

Strain: Haloferax volcanii

Number of amino acids: 476

Molecular weight: 51384.2

Theoretical pI: 4.30

Total number of negatively charged residues (Asp + Glu): 92

Total number of positively charged residues (Arg + Lys): 34

Instability index:The instability index (II) is computed to be 30.55

This classifies the protein as stable

Aliphatic index: 75.71

Grand average of hydropathicity (GRAVY): -0.471

Amino acid composition (%):

Ala	Arg	Asn	Asp	Cys	Gln	Glu	Gly	His	Ile	Leu	lys	Mcf	Phe	Pro	Ser	Thr	Trp	Tyr	Val
12.4	5.7	2.7	13.4	1.3	3.6	5.9	8.0	4.0	4.2	6.7	1.5	2.7	1.7	5.3	3.6	7.1	0.8	2.3	7.1

Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 Hours (Mammalian reticulocytes, in vitro)

Atom composition:

Carbon	Hydrogen	Nitrogen	Oxygen	Sulphur
2196	3416	636	753	19