Biochemical Properties


Protein Name: 5-formyltetrahydrofolate cyclo-ligase

Strain: Haloarcula vallismortis ATCC 29715


Number of amino acids: 242

Molecular weight: 26102.1

Theoretical pI: 4.49

Total number of negatively charged residues (Asp + Glu): 42

Total number of positively charged residues (Arg + Lys): 21

Instability index:The instability index (II) is computed to be 30.23

This classifies the protein as stable

Aliphatic index: 87.02

Grand average of hydropathicity (GRAVY): -0.248

Amino acid composition (%):

Ala Arg Asn Asp Cys Gln Glu Gly His Ile Leu lys Mcf Phe Pro Ser Thr Trp Tyr Val
12.8 6.6 1.2 9.5 0.4 2.9 7.9 6.2 2.5 3.3 6.2 2.1 1.2 1.7 7.9 3.3 8.3 1.7 1.7 12.8


Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 Hours (Mammalian reticulocytes, in vitro)

Atom composition:
Carbon Hydrogen Nitrogen Oxygen Sulphur
1145 1807 321 369 4